R&D decision governance

The decision governance layer for pharma R&D.

Decivio helps pharma teams turn fragmented clinical, safety, regulatory, operational, competitive and economic signals into explicit, traceable and executable development decisions.

A layer above your existing systems. Not another one to replace them.

Decision record · Frozen for board
Phase II → Phase III progression
CONDITIONAL GO
Decision questionAdvance under bounded conditions
GatekeepersSafety · Regulatory
Conditions3 defined · owners assigned
Competitive pressureCompetitor ahead · monitored
Re-reviewScheduled · trigger-based
EVIDENCE MATURITYRE-REVIEW ARMED
Efficacy signal · positive
Safety · monitoring trigger
Competitor readout · Q3
Capital cap · defined
The real bottleneck

More data. More AI. More signals. Still slow decisions.

Pharma R&D does not suffer from a lack of information. It suffers from the difficulty of converting fragmented, uncertain and sometimes contradictory signals into timely decisions that can be defended, executed and reviewed.

/01

Decisions fragmented across functions

Every function sees part of the truth, clinical, safety, regulatory, CMC, operations, portfolio. The program decision stays blurry across slides, meetings and partial evidence.

/02

Competition moves faster than internal alignment

A faster or better-differentiated competitor can erode a program's upside in months, while the board is still aligning.

/03

Go by default, weakly conditioned

Programs continue by inertia. "Go" decisions too often lack explicit conditions, capital caps, triggers and owners.

/04

No discipline after the board

Once decided, follow-up is informal. Triggers are not tracked, re-reviews slip, and the same patterns repeat with no decision memory.

What Decivio does

From fragmented signals to a governed decision.

Decivio creates a structured Decision Object for each critical R&D arbitration, then turns it into board-ready outputs and post-decision governance.

Clinical & safety signals
Regulatory & CMC readiness
Competitive intelligence
Operational & recruitment data
Capital & portfolio context
One structured object Decision Object Question · evidence · contradictions · roles · scenarios · conditions
Board-ready Decision Brief
Decision Contract
Trigger Tracker & re-review
Decision Record & memory
The Decivio approach

Make the invisible parts of a decision visible.

Decivio brings evidence, strategic tension and accountability into one shared decision environment. The underlying method is calibrated to the program, the tollgate and the organization.

Clarify

Give every function a shared view of the question, the evidence and what remains uncertain.

Arbitrate

Surface the trade-offs that matter before they become delays, politics or implicit assumptions.

Govern

Turn the board's direction into a decision that remains traceable, actionable and reviewable.

Why now

Signals are accelerating. Decisions are not.

Development costs keep rising, AI multiplies the volume and speed of R&D signals, and late continuation still burns capital. The organizations that win will be those that convert signals into governed decisions fastest.

$2.23B
Average cost to develop an asset across 20 top pharma companies in 2024, up from $2.12B the year before.
Deloitte, 2024
38 mo
Average duration of a Phase III trial, every month of indecision at this stage carries a material direct cost.
ASPE / NCBI, 2024
$7.7B
Capital burned in 2024 on trials for candidates later terminated across the top 20 biopharmas, much of it after late, weakly conditioned continuation decisions.
Deloitte, 2024
Outcomes

What changes with a decision layer.

Decivio does not claim to eliminate scientific failure. It targets avoidable value leakage: delayed decisions, implicit continuation, unresolved contradictions, underweighted competition and weak post-decision follow-up.

Clearer decision questions, framed before the debate
Faster cross-functional alignment with explicit roles
Contradictions and conditions made visible before the board
Competitive pressure integrated into the recommendation
Capital at risk made visible, including the cost of indecision
Board-ready decision artifacts, not just slides
Post-decision triggers, owners and re-review discipline
A growing decision memory across programs and boards
Start with one decision

Test Decivio on a real tollgate, in 10 to 12 weeks.

Apply Decivio to one upcoming tollgate and discover what changes when evidence, alignment and follow-through become one governed process.